Fig. 1.
![Fig. 1. Proliferation of MO7e cells in response to SCF correlates with c-kit receptor dimerization detected by FRET. MO7e cells were washed to remove GM-CSF and resuspended at a concentration of 1 × 105 cells/mL in IMDM suppplemented with 10% FCS and various concentrations of SCF (0 to 1,000 ng/mL; •), or 104D2 (0.5 μg/mL). After a 3-day incubation at 37°C, the number of viable cells was counted. The data represent the mean (± standard error of mean [SEM]) of triplicate values from one experiment. The wells supplemented with 104D2 contained 1.1 ± 0.2 × 105 MO7e cells/mL on day 3.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/91/3/10.1182_blood.v91.3.898/3/blod4031801.jpeg?Expires=1735554768&Signature=3dZXSs7Ooeqii41f4gPiYI9x-d0jTljczOggC57j8z6DM3sVLLIaroNHgPBkw2ac2y2vROrmd0jXd47NRDrjT8GV94xunY6kiD0RTS41JL-p5tsR5EH7GOS6eNPQxUkZgWc2cti1QHdVTQWzBMtV4ObLIMgIERheURi30~L5d7vQnw4e2ixhlLJISc5fWyKPuew5yHryrYiMcYsqPa1H1UyaW~uy8TjeOgtF8F6hAJ9Nxc0cqlZkCiAjPQR0o0Rr5vSLwIUqr9VcIwTmKYjaZ1x6lGuvn71BPg03X9kYjL9xaILLHI2dE2kz-v5tbCLIxQIg6cevhwxfvLurKT2WCA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Proliferation of MO7e cells in response to SCF correlates with c-kit receptor dimerization detected by FRET. MO7e cells were washed to remove GM-CSF and resuspended at a concentration of 1 × 105 cells/mL in IMDM suppplemented with 10% FCS and various concentrations of SCF (0 to 1,000 ng/mL; •), or 104D2 (0.5 μg/mL). After a 3-day incubation at 37°C, the number of viable cells was counted. The data represent the mean (± standard error of mean [SEM]) of triplicate values from one experiment. The wells supplemented with 104D2 contained 1.1 ± 0.2 × 105 MO7e cells/mL on day 3.
