Fig. 2.
Effect of TM on tissue factor-induced coagulation. Normal plasma (A) and protein C–deficient plasma (B) were incubated with 8.3 (▪), 16.7 (▴), or 25 nmol/L (▾) TM or with buffer (○). Clotting was initiated by adding recombinant tissue factor (Innovin, diluted by a factor 3 × 104) and calcium required for recalcification, and the formation of fibrin was measured in time as the change in turbidity at 405 nm.
