Dose-response curve of inhibition of thromboplastin-induced coagulant activity of baboon plasma by increasing concentrations of DEGR VIIa. A baboon thromboplastin standard curve was constructed using dilutions of baboon thromboplastin in normal baboon plasma. Active site inhibited fVIIa was added to 1:5 dilution of thromboplastin (100%) and the clotting times obtained were converted to thromboplastin activity using the standard curve. The plot was then obtained by plotting DEGR VII concentration versus thromboplastin activity.