Overall survival and survival by category of organ involvement. With median follow-up of 24 months (12 to 38), 17 of 25 patients (68%) survived, and the median survival has not yet been reached as depicted in (A) a Kaplan-Meier plot showing the 95% confidence interval (CI; proportional survival 0.65, 95% CI 0.48 to 0.88). (B) Survival by predominant organ involvement is shown. Total and mean times of follow-up for the three cohorts are 149 and 21.3 months (renal, n = 7), 225 and 22.5 months (other, n = 10), and 101 and 12.6 months (cardiac, n = 8). Patients without predominant cardiac involvement had better overall survival than cardiac patients (one-tailed Fisher's exact test, P < .05).