American Society of Hematology

Fig. 1.

$Fig. 1. Telomere shortening with age and in AA. Southern blot ofRsa I-digested genomic DNA from unfractionated peripheral blood leukocytes, probed with (TTAGGG)4. Positions of molecular weight markers are shown on the left. Tracks 1 through 5, normal donors: 1, age 29 years; 2, age 28 years; 3, age 90 years; 4, age 73 years; 5, age 66 years. Tracks 6 through 8, patients with acquired AA: 6, age 30 years, 99 months from diagnosis; 7, 43 years, 53 months from diagnosis; 8, 37 years, 4 months from diagnosis.$

Telomere shortening with age and in AA. Southern blot ofRsa I-digested genomic DNA from unfractionated peripheral blood leukocytes, probed with (TTAGGG)_4. Positions of molecular weight markers are shown on the left. Tracks 1 through 5, normal donors: 1, age 29 years; 2, age 28 years; 3, age 90 years; 4, age 73 years; 5, age 66 years. Tracks 6 through 8, patients with acquired AA: 6, age 30 years, 99 months from diagnosis; 7, 43 years, 53 months from diagnosis; 8, 37 years, 4 months from diagnosis.

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