Summary of the methylation status of CpG sites in Qp region in eBL tumors. The top panel shows the structure of Qp and Fp. The region from CpG sites #8 to #15 corresponds to the minimal region required for Qp function.30-32 The CAAT and TATA box for Fp and an inverted CCAAT box for Qp are labeled. The transcription initiation sites of Qp (EBV coordinate 62422) and Fp (EBV coordinate 62230) are indicated. The binding sites for EBNA1 are shown by boxes. (m) indicates methylated CpG sites, (-) indicates unmethylated CpG sites.