Fig. 2.
Effect of Rap on the [3H]thymidine incorporation by various T-cell lines that are exponentially growing. HTLV-I–infected (TL-Oml, MJ, MT-2, ED-40515[−]) or -uninfected (Molt4, HPB-ALL, HSB-2, Jurkat) T-cell line cells kept in an exponentially growing phase were cultured in fresh RPMI 1640 medium containing 10% FCS at low concentrations of cells with or without 10 nmol/L Rap for 48 hours. The [3H]thymidine uptake by cultured cells for the last 6 hours was measured. Each column represents the means ± SD of triplicate samples. Three independent experiments gave similar results.