Normal platelet aggregation induced by CRP-XL in PRP from a von Willebrand disease type 3 patient and from a control (A). Normal binding of fibrinogen to vWF-deficient platelets and to control platelets in vWF-deficient plasma activated with CRP-XL, measured by flow cytometry using FITC-labeled fibrinogen (B). Fluorescence of unstimulated control platelets is defined as 1. Data shown are representative of two similar experiments.