Fig. 4.
![Fig. 4. Induction of erythroid colony formation from fetal liver CFU-E progenitors requires the expression of the EpoR. Day-12.5 fetal liver cells dissected from EpoR−/− embryos (A) or from wild-type embryos (B) were infected with viruses encoding β-galactosidase (control), gp55-P, gp55-A, and murine EpoR. The retroviral vector used is indicated (SFFV or pBABE). Cells were assayed in CFU-E assays in the absence or presence of EPO or (in the right-most panel of [A]) in the presence of Epo and SF. Data represent the average of two experiments, each performed in duplicate; the variation was less than 20%.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/91/4/10.1182_blood.v91.4.1163/4/blod4044104.jpeg?Expires=1735531207&Signature=NJu3XYS5Szi1jyqHvBXr3nokrLHycO7zuTTwd09FGVVIEE~qzbqFCGQoZ5X2zhrJoiHIgngDvyKwuquapUqPxtaQeKeDOrBzXtU89YYEH5vrnTIXSzhHTEZJvlFPjEymKR6f~IQWe7s10-kp-iJbUbZ2xpo9v5QCYp94HHNmhot0lLQPm1fTtF~Z38rPpdnSqxlrUozrFuDCYLVxn8XwRcfBLyNLYVNjZBgSWxWVSOY2lqTsrDhsuiXxBO~ZzAK~tOHszJ43uz7g1Wkr9dSK~uOKKiXX~wjP1jFTIlPbXMFGlo4vcwkhfLsknJz4xYCK1jwW8Kmi9B01-aNVgP2yYw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Induction of erythroid colony formation from fetal liver CFU-E progenitors requires the expression of the EpoR. Day-12.5 fetal liver cells dissected from EpoR−/− embryos (A) or from wild-type embryos (B) were infected with viruses encoding β-galactosidase (control), gp55-P, gp55-A, and murine EpoR. The retroviral vector used is indicated (SFFV or pBABE). Cells were assayed in CFU-E assays in the absence or presence of EPO or (in the right-most panel of [A]) in the presence of Epo and SF. Data represent the average of two experiments, each performed in duplicate; the variation was less than 20%.
