Tyrosine phosphorylation in normal (lanes 1 to 4) and Scott syndrome platelets (lanes 5 to 8). Lanes 1 and 5 represent unstimulated platelets; lanes 2 and 6, platelets stimulated with 4 nmol/L thrombin; lanes 3 and 7, platelets treated with 70 nmol/L thapsigargin and subsequently activated with 4 nmol/L thrombin; lanes 4 and 8, platelets activated with 10 μg/mL collagen.