Fig. 1.
Fig. 1. (A) Southern blot of t(14;18) major breakpoint region PCR products to assess assay sensitivity. Dilutions of positive control (SU-DHL-6) DNA in negative control (HL60) DNA. 1, 1:103; 2, 1:104; 3, 1:105; 4, 1:106; 5, HL60 DNA; arrow, t(14;18) PCR product. (B) Example of Southern blot of t(14;18) major breakpoint region PCR products from patient biopsy specimens: 1, RL-7 positive control; 2, negative control; 3 to 8, patient PCR products. Size standards at left in base pairs.

(A) Southern blot of t(14;18) major breakpoint region PCR products to assess assay sensitivity. Dilutions of positive control (SU-DHL-6) DNA in negative control (HL60) DNA. 1, 1:103; 2, 1:104; 3, 1:105; 4, 1:106; 5, HL60 DNA; arrow, t(14;18) PCR product. (B) Example of Southern blot of t(14;18) major breakpoint region PCR products from patient biopsy specimens: 1, RL-7 positive control; 2, negative control; 3 to 8, patient PCR products. Size standards at left in base pairs.

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