Scatchard analysis of t-PA binding to fibrin. Scatchard plots derived using data from binding isotherms (Fig 2). Binding in the absence (▵, ◊, □; ------) and presence (▴, ⧫, ▪; ______) of ultrasound is shown. (A) Surface-immobilized fibrin. (B) Non-crosslinked fibrin. (C) Crosslinked fibrin.