Localization of probes from chromosome 5q or 7p used for FISH detection of the breakpoints in case 1 with a t(5;12)(q31;p13) (A), case 3 with a t(7;12)(p15;p13) (B), and case 4 with a t(7;12)(p12;p13) (C). Abbreviations: (A) Asterisk (*) indicates hybridization with a der(12)t(5;12); (B) plus sign (⁺) indicates hybridization with a der(7)t(7;12) and ^sindicates split signal on der(7) and der(12); (C) ° indicates hybridization with a der(12)t(7;12), and asterisk (*) indicates hybridization with a der(7)t(7;12); ◂ indicates position of breakpoint.