TF inhibits the binding of Glu-plasminogen to cells.¹²⁵I-Glu-plasminogen (100 nmol/L) was added to HUVECs (A) or trophoblasts (B) in the presence of the indicated concentrations of TF or 15 mmol/L 6-AHA and the cell-associated radioactivity was measured. The results are expressed relative to the binding of radiolabeled plasminogen in the absence of TF. The mean ± SD of three separate experiments performed in triplicate is shown.