Fig. 1.
Effect of F2 on radioactive choline, ethanolamine, and hypoxanthine incorporations into the macromolecules of P falciparum-infected erythrocytes. Infected cells (10% hematocrit, 3.6% parasitemia) were incubated for 4 hours at 37°C in the absence (control) or presence of the indicated concentrations of F2 and in the presence of 10 μmol/L (3H)choline (1.2 μCi) (•), 2 μmol/L (3H)ethanolamine (0.3 μCi) (▴), and trace concentrations of (3H)hypoxanthine (1 μCi) (▪). The reaction was stopped by cell filtration as described in the Materials and Methods. Results are expressed as a percentage of the control (without drug) ± SEM.
