BMT at peak of acute disease. Clinical course is reported in terms of the mean clinical score, which is the total score for animals in a group divided by the number of animals in the group. Statistical analysis by the Student t-test on day 140 showed significant clinical improvement in the treatment groups, withP = .009 for TBI, P = .004 for Cy/TBI, andP = .01 for MP/TBI. Bold arrow indicates time of treatment. Arrow 1 indicates killing of 3 animals from each group for proliferation and ELISA assays. Arrow 2 indicates killing of 1 animal from each group for histology and use of 3 animals from each group for DTH.