IFNγ production in splenocytes from WT and ICE-deficient mice. Splenocytes from WT (•) or ICE-deficient (○) mice were incubated with the indicated concentration of LPS (A), zymosan (B), or Con A (C) for 24 hours and levels of IFNγ measured. Data are the mean ± SEM of 9 mice per group. *P < .05; **P < .01 versus WT by factorial ANOVA.