Allergic pleurisy in wild-type, NFAT1^−/−, and parental strain mice. Shown are the total number of eosinophils in the pleural cavity of C57BL/6, 129/Sv, wild-type (+/+), and NFAT1^−/− mice sensitized with OVA and challenged in the pleural cavity with PBS or OVA. Data are expressed as mean ± SEM of values from 5 mice. (*) Indicates significantly greater response relative to wild-type mice (P < .05).