Effect of flavopiridol therapy in systemic leukemia and lymphoma xenografts. (a) Kaplan and Meier survival curve of SCID mice bearing systemic human acute lymphoblastic leukemia (Nalm/6) treated with flavopiridol 7.5 mg/kg IV every other day × 5 at days 3 to 7, and repeated again at days 17 to 21 posttransplantation of cells (•). Control mice (▪) received the vehicle 1% DMSO in NaCl. (b) Kaplan and Meier survival curve of SCID mice bearing systemic human AS283 human lymphoma after one 5-day cycle of flavopiridol bolus IV therapy from days 3 to 7 posttransplantation of cells (•). Control mice received the vehicle (▪).