Fig. 3.
EBV clonality in lymphoma tissues assessed by Southern analysis. Genomic DNA was digested with BamHI, separated on an agarose gel, and transferred to a nitrocellulose membrane. The membrane was hybridized with 32P-labeled B95-8 fragment containing the LMP open reading frame, washed, and visualized by autoradiography. Tumors 1 and 2 were derived from different lymph nodes of case 1; one tumor specimen was derived from case 2. B95-8 and Raji cell lines were used as EBV–positive controls; Louckes cell line was used as an EBV–negative control.
