Expression of LRP in initial and relapsed childhood ALL. The median FI of each group is depicted by a square; the upper and lower diamonds represent the 75th and 25th percentile, respectively. Data are based on 112 initial, 22 first relapse (1st), and 7 multiple relapse (≥2nd) samples. The difference between the FI of multiple relapse samples and initial or first relapse samples is significant (P = .026 and P = .050, respectively).