![Fig. 2. Mobilization of CFU into the PB after growth factor administration. (A and B) The frequency of CFU-GM and CFU-GEMM (per 105 cells) in PB after 2, 4, 6, and 10 days growth factor treatment, respectively. (C and D) The absolute number of CFU-GM and CFU-GEMM per mL of PB (PBMNC count multiplied by CFU frequency) after 2, 4, 6, and 10 days growth factor treatment, respectively. PBMNC from four mice were pooled within each group for CFU assays (see Materials and Methods). In all growth factor-treated groups, total CFU per mL of PB and CFU frequency per 105 cells had almost returned to pretreatment values 1 week postgrowth factor treatment (data not shown). This experiment was performed twice giving very similar results (only differing in the route of injection [IP] and dosage of G-CSF and GM-CSF [5 μg/mouse/d]).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/9/10.1182_blood.v90.9.3781/4/bl_0001f2.jpeg?Expires=1735848191&Signature=yf~1Xq8Z-pFEwa3VVkmuc92N~GhzWZ8CU0CY4UDWOFwcjqZGMQd25XqKzPVjqem94HRVuBHGde8kb8tNsfWbUcglES4A6bmog28qwDMXaGAmIGDp8ftjoiIRs1rLWoa3edwh84JjjY3uiwr~ACXxkPPrIF8I8wPYdLxKUkuwsTcCwkWfE039Dz8uLOXHgg8t1JakJdtIEdIbym6En3iLvF70FKjFmKknB15gs1GTvDm4Z6HteOrdq8OeRMQ0bnoq8vIiuvsL3f69XbI~WJtLGPhob7Cyz5gkMSOaJyBqlq8mtQmw1fuCAzD~MjEtoA2TqjUEzZpV61iS3JOGkqGZjA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Mobilization of CFU into the PB after growth factor administration. (A and B) The frequency of CFU-GM and CFU-GEMM (per 105 cells) in PB after 2, 4, 6, and 10 days growth factor treatment, respectively. (C and D) The absolute number of CFU-GM and CFU-GEMM per mL of PB (PBMNC count multiplied by CFU frequency) after 2, 4, 6, and 10 days growth factor treatment, respectively. PBMNC from four mice were pooled within each group for CFU assays (see Materials and Methods). In all growth factor-treated groups, total CFU per mL of PB and CFU frequency per 105 cells had almost returned to pretreatment values 1 week postgrowth factor treatment (data not shown). This experiment was performed twice giving very similar results (only differing in the route of injection [IP] and dosage of G-CSF and GM-CSF [5 μg/mouse/d]).
