(A) Micrograph of lung tissue 48 hours after intranasal infection with 1 × 10³ CFU of K pneumoniae B5055 and pretreatment with G-CSF (50 μg/kg sc) at −48 hours, −36 hours, −24 hours, and −12 hours before infection. Peribronchiolar neutrophils without destruction of lung parenchyma. H&E; original magnification ×150. (B) Splenic abscesses in the red pulp containing numerous gram-negative bacilli are found. H&E; original magnification ×370. (C) Confluent hepatic necroses. H&E; original magnification ×150.