MMC sensitivity of FAA-retroviral transduced lymphoblasts. Plot of cell survival of FAA parental and retroviral-transduced cell lines after incubation with varying concentrations of MMC. MMC sensitivity of lymphoblasts derived from a normal individual is shown. All data points are the results of quadruplicate determinations (SEM < 5%). Open symbols represent FAA mutant parental cell lines, closed symbols represent retroviral-transduced cell lines, (⋅⋅•⋅⋅) indicates retroviral-transduced cell line with vector FAA/4.3 (clone 6.9). Normal lymphoblasts are represented by the solid line (─). ( — ○ — ), HSC 72; (– –▵– –), EUFA 528; ( — • — ), HSC 72/Retro17; (⋅⋅⋅•⋅⋅⋅), HSC 72/Retro6.9; (– –▴– –), EUFA 528/Retro29; ( — ▪ — ), normal; (– –▿– –), EUFA 471; ( — ⋄ — ), EUFA 005; ( — □ — ), EUFA 471/Retro17; ( — ▾ — ), EUFA 005/Retro17.