Fig. 4.
Cell-cycle kinetics of corrected FAA cells. The effect of mitomycin C on DNA flow cytometry histograms of retroviral-transduced lymphoblasts. The transduced and parental FAA cell line EUFA 528 were incubated in the presence and absence of MMC. Cells were harvested, stained with propidium iodide, and DNA histograms obtained 48 hours after cells were exposed to 100 nmol/L MMC. EUFA 528, parental FAA line; EUFA 528/29, retroviral-transduced cell line. −/+ refers to the presence and absence of MMC. The percentage of cells in the G1 and G2/M fractions are indicated.