American Society of Hematology

Fig. 4.

$Fig. 4. Composition of the human CD45+ cell population in chimeric SCID mice stained for the human markers shown in Fig 3. Results (average ± SD) are those of 23 mice in total, transplanted with unfractionated UCB (A), purified CD34+(B), CD34+CD38− (C), and CD34− (D) grafts derived from 5 UCB samples. The percentage of cells in each subset was expressed relative to the percentage of CD45+ cells present in the BM of each mouse. The percentage of chimerism ranged between 10% and 40% for the data shown in (A) through (C) and between 1% and 15% for the data shown in (D).$

Composition of the human CD45⁺ cell population in chimeric SCID mice stained for the human markers shown in Fig 3. Results (average ± SD) are those of 23 mice in total, transplanted with unfractionated UCB (A), purified CD34⁺(B), CD34⁺CD38⁻ (C), and CD34⁻ (D) grafts derived from 5 UCB samples. The percentage of cells in each subset was expressed relative to the percentage of CD45⁺ cells present in the BM of each mouse. The percentage of chimerism ranged between 10% and 40% for the data shown in (A) through (C) and between 1% and 15% for the data shown in (D).

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