Fig. 3.
LMP1 expression and tumorigenicity of LMP1-transfected BL41 cells. (A) Western blot analysis of LMP1 expression in parental, B95-8-EBV–converted, and LMP1-transfected BL41 cells. Cell extracts from 2 × 105 cell equivalents were electrophoresed through 8% Tris-glycine gels, transferred onto nylon membranes, and probed with a murine MoAb to LMP1 (S12). (B) Growth curves of tumors induced by subcutaneous inoculation of LMP1 or vector-transfected BL41 cells. Growth curves of tumors from vector-transfected BL41 cells and LMP1-transfected BL41 cells are depicted for individual mice.