L11 blocks recruitment of monocytes and neutrophils to the thioglycollate-inflamed peritoneum. Balb/c mice were injected (IV) with 250 μg of control IgG or with L11 and then injected with thioglycollate to induce peritonitis. Recruited cells were harvested, stained with monocyte and neutrophil markers, and analyzed by flow cytometry. The total number of monocytes (A) and neutrophils (B) recruited to the peritoneal cavity at 4, 24, and 72 hours was determined. Peripheral blood was collected at each time point, stained as in (A) and (B) and the total number of leukocytes, as well as the relative number of monocytes (C) and neutrophils (D) was determined. Data shown are the mean and standard error of the total number of cells per animal found in three animals per condition in each of three independent experiments (N = 3).