Fig. 6.
Nuclear DNA fragmentation in the p210bcr-abl-expressing UT7/9 cells. Nuclei from UT7/9 cells in which DNA was labeled with [14C]-thymidine were incubated for 30 minutes at 37°C with buffer alone (Buffer) or 100 μmol/L etoposide alone (VP-16) or triton-soluble extracts from either untreated (U937) or etoposide-treated (100 μmol/L for 3 hours; U937/VP) U937 cells. Apoptotic DNA fragmentation was then measured by filter elution assay. Results are the mean ± SD of two different experiments performed in duplicate.