Inhibitory effects of MoAbs against L-selectin (LAM1-3), E-selectin (7A9), and CD18 (IB-4) on the respiratory burst of neutrophils under shear stress (left histograms) and static conditions (right histograms). Control experiments were performed in the presence of buffer instead of MoAbs (control), or the MoAb LAM1-14, recognizing a nonfunctional epitope of L-selectin (LAM1-14). Endothelial cells were preactivated with IL-1 (30 ng/mL) for 4 hours. Neutrophils on resting endothelial cells in the absence of ICs, were used as control (filled histograms). The data are representative of three experiments.