Fig. 9.
Hypoxic reduction of HIF-1α mRNA levels in mouse liver. Three mice each were exposed to 7.5% O2 for 0 to 72 hours and liver RNA was analyzed by Northern blotting. Shown are the ratios of HIF-1α mRNA and aldolase A mRNA, respectively, and the ribosomal protein L28 mRNA (mean ± SD).