Fig. 3.
Fig. 3. Autoradiographs of Msp I—digested DNA, hybridized to the 149b19 probe on chromosome 6 and aBCL-1 probe. ALL patient 56 (lane 1) and patient 64 (lane 3) had LOH on chromosome 6 in the PCR analysis. Lane 2 contains normal DNA and lane 4 contains DNA from an ALL patient without LOH. There is a reduced signal in DNA from patients 56 and 64, indicating a hemizygous deletion of the 149b19 marker.

Autoradiographs of Msp I—digested DNA, hybridized to the 149b19 probe on chromosome 6 and aBCL-1 probe. ALL patient 56 (lane 1) and patient 64 (lane 3) had LOH on chromosome 6 in the PCR analysis. Lane 2 contains normal DNA and lane 4 contains DNA from an ALL patient without LOH. There is a reduced signal in DNA from patients 56 and 64, indicating a hemizygous deletion of the 149b19 marker.

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