IL-8 production by isolated polymorphonuclear cells (PMN) after in vitro activation with LPS from different origins (Escherichia coli: E.c.; Neisseria meningitidis: N.m.) or with heat-killed, group A streptococcus. The data are the mean of experiments performed with isolated PMN from healthy controls (n = 13), post-CPB patients (n = 9), and patients with sepsis (n = 11). P values correspond to statistical analysis between post-CPB or sepsis groups versus control one.