Fig. 5.
Correlation of CD44-6v isoform expression with survival of AML patients. Survival curves of AML patients according to the expression of CD44-6v on leukemic cells at diagnosis, have been computed using the Kaplan-Meier method.38 Statistical comparisons between curves were based on log-rank tests. (A, B, and C) Overall survival curves of AML patients treated by conventional chemotherapy36 (anthracyclin plus cytosin arabinosine). (D and E) Disease-free survival curves of AML patients induced in complete remission by conventional chemotherapy. M1/M2, myeloblastic AML; M4, myelomonocytic AML; M5, monoblastic AML. Significant numbers have been obtained by grouping M4 and M5 patients for overall survival, but not for disease-free survival analysis.