Fig. 5.
Percentages of CD19+ and CD33+cells 6 to 9 weeks after injection of CB CD34+ cells in 3 goups of NOD-SCID mice.
Percentage of cells expressing CD19 or CD33 recovered from the bone marrow of NOD-SCID mice that were killed 6 to 9 weeks after tail injection of fresh CD34+ CB cells (primary CD34+ cells that did not undergo amplification and transduction steps), or cultured CD34+ cells that underwent LZRF-EGFP transduction (control cells), or CD34+ cells tranduced with the LZRS-Ik6-EGFP retroviral vector (test cells). Detailed analysis of engraftment is provided in Tables 1 and2.