Prognostic significance of RT-PCR in APL.

This Kaplan-Meier plot shows the probability of disease-free survival for newly diagnosed patients with at least 2 negative RT-PCR assays or fewer than 2 negative assays after completion of therapy. Tick marks indicate the time of last follow-up. The probability of remaining leukemia-free after 5 years for patients with at least 2 negative assays was 92%. All patients with a confirmed positive test relapsed after a median of 9 months (P < .0001).