Caspase processing in B-CLL cells.

(A) Processing of procaspase 8 (open bars) and procaspase 3 (hatched bars) in B-CLL samples after 24-hour treatment, estimated by Western blotting. Procaspase band intensities were normalized to actin, and the ratio was set to 1.0 for the control for each sample. (B) Processing of PARP to its p85 fragment in B-CLL samples after 24-hour treatment. p85 PARP was compared with actin levels, and the ratio was set to 1.0 for the control in each sample. Student t test was carried out using procaspase-actin or p85 PARP–actin ratios (*P = .05; **P > .05; †.01 <P < .05; ††P < .01).