Fig. 2.
Immunohistochemical staining of RANK protein in primary lymphoid tumors.
RANK was highly expressed in H/RS cells of a lymph node involved with nodular sclerosis (A) and mixed cellularity (B). The surrounding infiltrating cells rarely, but weakly, expressed RANK. Section from a lymph node involved with B-cell lymphocytic lymphoma (C) and from a benign hyperplastic lymph node (D) showing that RANK was rarely, but weakly expressed in these sections.