Fig. 2.
Cleavage of in vitro–translated PARP. [35S]-PARP was incubated for 1 hour at 37°C with cell lysates from untreated or from 1μmol/L RA-treated (A) NB4 and (B) U937/PR9 cells induced (+) or not (−) by 100 μmol/L Zn to express PML/RARα. One hundred micromoles per liter DEVD was added as indicated. Arrow indicates the 85-kD PARP cleavage product.