BAL fluid TNF-α and IFN-γ concentrations after BMT. CBA mice received BMT as in Fig 1 (syngeneic □, allo TCD BM alone ▩, allo TCD BM and T cells ▪). BAL fluid was obtained 6 weeks after BMT and analyzed for TNF-α and IFN-γ concentrations as described in Materials and Methods. Both TNF-α and IFN-γ were significantly increased in the BAL fluid from mice receiving allogeneic BM and T compared with syngeneic controls (**P < .01). BMT with TCD BM only lead to a 50% reduction in TNF-α (#P = .01) but not IFN-γ, and levels of both cytokines remained significantly elevated compared with syngeneic controls (*P < .05). Data are expressed as mean ± SEM. (n = 8 to 12 per group).