Fig. 5.
Allogeneic transplant recipients with GVHD showed a reduced pulmonary influx of lymphocytes. BAL cell numbers of mock-infected mice and mice 7 days after intranasal HSV-1 infection were determined. (A) Total lymphocytes recovered by BAL. (B) CD8+ T cells recovered by BAL. Numbers are expressed as the multiple of the cells recovered in infected versus mock-infected mice. The numbers were calculated from the percentages determined by FACS analysis. Data represent means ± SE of individual or pooled BAL samples, derived from at least two separate experiments. Numbers of mice were as shown in Fig 4. The asterisks indicate a significant difference from both normal CBA and allogeneic No GVHD (P < .04; Student's t-test). The error bar for the allogeneic no GVHD group in (B) falls within the symbol.