Figure 7.
As2O3 inhibits anti-DNA autoantibody and RF production in MRL/lpr mice. IgG1, IgG2a, IgG2b, and lgG3 anti-DNA autoantibodies, and IgM, IgG and IgG3 RF levels were quantified by ELISA in the sera (dilution, 1:1600) of 4-month-old MRL+/+ and MRL/lpr mice that had been treated daily for 2 months with As2O3 (5 μg/g) or PBS. Results are from 10 individual mice per group. Error bars indicate SE.