Figure 5.
IkL/L pDC precursors respond to Flt-3 signaling. (A) 120G8+ BM cells were analyzed for Flt-3 expression. The pDC population is indicated by the white histograms. Gray histograms indicate the isotype controls. Results are representative of 5 experiments. (B-C) Unfractionated BM cells were cultured with Flt-3L over a 9-day period. (B) Contour plots show B220 and 120G8 expression of CD11c+ cells after 7 days of culture. (C) Graph shows the percentage of 120G8+ cells among total cells for the indicated number of days. One representative experiment of 5 is shown.