Effects of in vivo IFN-γ treatment on peripheral white blood cell (WBC) counts and bone marrow cellularity. (A) Peripheral nucleated cell counts were obtained from experimental mice following completion of IFN-γ treatment (closed symbols) or the phosphate-buffered saline vehicle, PBS (open symbols). Each symbol represents total nucleated white blood cells from individual mice. Bars represent the mean WBC count of all experimental mice in the respective treatment group. *P < .01 comparing white blood cell counts of IFN-γ–treated mice to vehicle-treated control mice with the same genotype. (B) BM cellularity following IFN-γ treatment. Symbols represent bone marrow cellularity of individual mice. Bars represent the mean BM cellularity of all mice in the experimental group. *P < .01 comparing bone marrow cellularity of IFN-γ–treated mice versus vehicle-treated controls of the same genotype.