Relationship between urinary II-dehydro- TXB₂ levels and their potential determinants in polycythemia vera patients. (A) Correlation between VWF levels and urinary 11-dehydro-TXB₂ excretion in 29 polycythemia vera patients according to quartiles of ECFCs. ● represents subjects in the first and second quartiles for ECFC number. ○ represent subjects in the third and fourth quartiles for ECFC number. ¦ and mark the boundaries of median values of both VWF and 11-dehydro-TXB₂. (B) Urinary 11-dehydro-TXB₂ levels according to quartiles of ECFC number in polycythemia vera patients. Box and whisker plots of urinary 11-dehydro-TXB₂ levels divided according to quartiles of ECFC number. , representing the 95th percentile of 11-dehydro-TXB₂ values in the control group, discriminates subjects with low versus high 11-dehydro-TXB₂ values. Overall significance (by Kruskal-Wallis test): P = .043. (C) ADMA levels in polycythemia vera patients, according to 11-dehydro-TXB₂ values below or above the 95th percentile of control values. Box and whisker plots of plasma ADMA levels in PV patients, stratified according to 11-dehydro-TXB₂ values below or above the 95th percentile of 11-dehydro-TXB₂ values in the control group.