Live mf of B malayi down-regulate mRNA expression of TLR3, TLR4, TLR5, and TLR7 in mhDCs. mRNA expression in mhDCs and mhDCs exposed to live mf for 48 hours is represented as 1/average ΔCT. The higher the number, the higher the expression of the gene. Results of 7 to 16 independent experiments are shown; each data point and line represent one donor within an experiment. 1/average ΔCT less than 0.041 in the gray box represents no mRNA expression.