Figure 3
Figure 3. Correlation of survival and methylation levels for chromosome 17q25 gene region. Depicted are the methylation results for a region on chromosome 17q25 with the strongest prediction for patient survival. The top panel shows methylation values in the context of their genomic location. Red vertical bars depict the location of CpG units. Green boxes indicate a conserved transcription factor binding site. For every data series the methylation values in this group are averaged and the mean is displayed for each analyzed CpG unit. Shown are the values for patients who have been classified by the methylation prediction model into a favorable outcome class (red), a poor outcome class (blue), and normal blood samples (orange). The second panel indicates the location of the amplification targets. The third (lowest) panel depicts the gene structure. The methylation ratio values indicate that patients in the good outcome class have methylation levels similar to the normal control samples.

Correlation of survival and methylation levels for chromosome 17q25 gene region. Depicted are the methylation results for a region on chromosome 17q25 with the strongest prediction for patient survival. The top panel shows methylation values in the context of their genomic location. Red vertical bars depict the location of CpG units. Green boxes indicate a conserved transcription factor binding site. For every data series the methylation values in this group are averaged and the mean is displayed for each analyzed CpG unit. Shown are the values for patients who have been classified by the methylation prediction model into a favorable outcome class (red), a poor outcome class (blue), and normal blood samples (orange). The second panel indicates the location of the amplification targets. The third (lowest) panel depicts the gene structure. The methylation ratio values indicate that patients in the good outcome class have methylation levels similar to the normal control samples.

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