Box-plot analysis of NMF values. Comparison of NMF values among subset 4 rearrangements (subset 4, IGHV4-34/IGKV2-30)17,18 versus (1) all other rearrangements included in the analysis (nonsubset 4); (2) subset 16 rearrangements (subset 16, IGHV4-34/IGKV3-20)17,18 ; IGHV4-34 rearrangements from cases expressing the common IgM/D isotype (M 4-34); subset 2 rearrangements (subset 2, IGHV3-21/IGLV3-21)17,18 ; and subset 8 rearrangements (subset 8, IGHV4-39/IGKV1(D)-39).17,18