Blood levels of glucose and AUC for glucose during OGTT after islet transplantation in BM and liver. Glucose tolerance in an OGTT was measured at 1, 3, 6, and 12 months after islet transplantation into BM or liver. Shown are the OGTT glycemic profile and AUC for glucose in mice that achieved euglycemia (28 of 47 for intra-BM and 10 of 32 for intraliver). The yellow shaded area represents the range of values in healthy control mice (Ctrl, n = 11). Data are expressed as mean for glycemic profile and boxplots for glucose AUC. Statistical analysis was performed using 1-way ANOVA test, followed by Bonferroni post hoc t test. *P < .01 versus control.