CsA treatment alters absolute lymphocyte counts during infection. We used flow cytometry and an automated hematologic analyzer to determine absolute lymphocyte counts 6 weeks after infection. (A) The 20 mg/kg CsA–treated rabbits had increased absolute T cell, CD4⁺, and CD8⁺ T cells. (B) The 20 mg/kg CsA–delayed treatment rabbits had increased CD4/CD8 T-cell ratios due, in part, to a decrease in CD8⁺ T cells.